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Ca(2+)-dependent ATP release from A549 cells involves synergistic autocrine stimulation by coreleased uridine nucleotides

Extracellular ATP is a potent surfactant secretagogue but its origin in the alveolus, its mechanism(s) of release and its regulatory pathways remain unknown. Previously, we showed that hypotonic swelling of alveolar A549 cells induces Ca(2+)-dependent secretion of several adenosine and uridine nucle...

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Autores principales: Tatur, Sabina, Groulx, Nicolas, Orlov, Sergei N, Grygorczyk, Ryszard
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277166/
https://ncbi.nlm.nih.gov/pubmed/17702822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.133314
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