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Synthesis, radiolabeling, and baboon SPECT imaging of 2β-carbomethoxy-3β-(3′-[(123)I]iodophenyl)tropane ([(123)I]YP256) as a serotonin transporter radiotracer.([(123)I]YP256) a potential serotonin transporter radiotracer)
To develop a potential SPECT probe to evaluate the integrity of the serotoninergic system (5-HTT) whose dysfunction is linked to several disease conditions such as Parkinson’s, Alzheimer’s diseases and depression, we report the synthesis, radiolabeling and in vivo baboon imaging of 2β-carbomethoxy-3...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276982/ https://ncbi.nlm.nih.gov/pubmed/18158943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2007.09.002 |
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