The pyrimidin analogue cyclopentenyl cytosine induces alloantigen-specific non-responsiveness of human T lymphocytes

Cyclopentenyl cytosine (CPEC) has been shown to induce apoptosis in human T lymphoblastic cell lines and T cells from leukaemia patients. In this study we have addressed the question of whether CPEC is able to decrease proliferation and effector functions of human alloresponsive T lymphocytes and in...

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Detalhes bibliográficos
Main Authors: Nikolaeva, N, Bemelman, F J, Yong, S-L, Verschuur, A, van Lier, R A W, ten Berge, I J M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Basic Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276945/
https://ncbi.nlm.nih.gov/pubmed/18062797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03557.x
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