Collective and Individual Functions of Leptin Receptor Modulated Neurons Controlling Metabolism and Ingestion

Two known types of leptin-responsive neurons reside within the arcuate nucleus: the agouti gene-related peptide (AgRP)/neuropeptide Y (NPY) neuron and the proopiomelanocortin (POMC) neuron. By deleting the leptin receptor gene (Lepr) specifically in AgRP/NPY and/or POMC neurons of mice, we examined...

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Hlavní autoři: van de Wall, Esther, Leshan, Rebecca, Xu, Allison W., Balthasar, Nina, Coppari, Roberto, Liu, Shun Mei, Jo, Young Hwan, MacKenzie, Robert G., Allison, David B., Dun, Nae J., Elmquist, Joel, Lowell, Bradford B., Barsh, Gregory S., de Luca, Carl, Myers, Martin G., Schwartz, Gary J., Chua, Streamson C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276717/
https://ncbi.nlm.nih.gov/pubmed/18162515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1132
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