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Collective and Individual Functions of Leptin Receptor Modulated Neurons Controlling Metabolism and Ingestion

Two known types of leptin-responsive neurons reside within the arcuate nucleus: the agouti gene-related peptide (AgRP)/neuropeptide Y (NPY) neuron and the proopiomelanocortin (POMC) neuron. By deleting the leptin receptor gene (Lepr) specifically in AgRP/NPY and/or POMC neurons of mice, we examined...

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Bibliographic Details
Main Authors: van de Wall, Esther, Leshan, Rebecca, Xu, Allison W., Balthasar, Nina, Coppari, Roberto, Liu, Shun Mei, Jo, Young Hwan, MacKenzie, Robert G., Allison, David B., Dun, Nae J., Elmquist, Joel, Lowell, Bradford B., Barsh, Gregory S., de Luca, Carl, Myers, Martin G., Schwartz, Gary J., Chua, Streamson C.
Format: Artigo
Language:Inglês
Published: The Endocrine Society 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276717/
https://ncbi.nlm.nih.gov/pubmed/18162515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1132
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