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Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery

BACKGROUND: Urinary exosomes containing apical membrane and intracellular fluid are normally secreted into the urine from all nephron segments, and may carry protein markers of renal dysfunction and structural injury. We studied effective methods for the collection, storage, and preservation of urin...

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Detalhes bibliográficos
Main Authors: Zhou, Hua, Yuen, Peter S.T., Pisitkun, Trairak, Gonzales, Patricia A., Yasuda, Hideo, Dear, James W., Gross, Peter, Knepper, Mark A., Star, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276656/
https://ncbi.nlm.nih.gov/pubmed/16501490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.ki.5000273
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