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Application of systems biology principles to protein biomarker discovery: Urinary exosomal proteome in renal transplantation

PURPOSE: In MS-based studies to discover urinary protein biomarkers, an important question is how to analyze the data to find the most promising potential biomarkers to be advanced to large-scale validation studies. Here, we describe a ‘systems biology-based’ approach to address this question. EXPER...

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Detalhes bibliográficos
Main Authors: Pisitkun, Trairak, Gandolfo, Maria T., Das, Samarjit, Knepper, Mark A., Bagnasco, Serena M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809079/
https://ncbi.nlm.nih.gov/pubmed/22641613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.201100108
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