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GSK-3β Targets Cdc25A for Ubiquitin-Mediated Proteolysis and GSK-3β Inactivation Correlates with Cdc25A Overproduction in Human Cancers
The Cdc25A phosphatase positively regulates cell cycle transitions; is degraded by the proteosome throughout interphase and in response to stress; and is overproduced in human cancers. The kinases targeting Cdc25A for proteolysis during early cell cycle phases have not been identified and mechanisti...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276649/ https://ncbi.nlm.nih.gov/pubmed/18167338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2007.12.002 |
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