Loading...

Metallothionein Expression Is Suppressed in Primary Human Hepatocellular Carcinomas and Is Mediated through Inactivation of CCAAT/Enhancer Binding Protein α by Phosphatidylinositol 3-Kinase Signaling Cascade

Reactive oxygen species (ROS) resulting from chronic inflammation cause liver injury leading to transformation of regenerating hepatocytes. Metallothioneins (MT), induced at high levels by oxidative stress, are potent scavengers of ROS. Here, we report that the levels of MT-1 and MT-2A are drastical...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Datta, Jharna, Majumder, Sarmila, Kutay, Huban, Motiwala, Tasneem, Frankel, Wendy, Costa, Robert, Cha, Hyuk C., MacDougald, Ormond A., Jacob, Samson T., Ghoshal, Kalpana
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276570/
https://ncbi.nlm.nih.gov/pubmed/17363595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-4433
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!