Glucocorticoid-induced Tumor Necrosis Factor Receptor Negatively Regulates Activation of Human Primary Natural Killer (NK) Cells by Blocking Proliferative Signals and Increasing NK Cell Apoptosis

Glucocorticoid-induced tumor necrosis factor receptor (GITR), found constitutively expressed on human primary natural killer (NK) cells at low levels was up-regulated upon stimulation by either Toll-like receptor ligand or NK cell growth factor, interleukin (IL)-15. cDNA microarray analysis showed t...

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Detalhes bibliográficos
Main Authors: Liu, Baoying, Li, Zhuqing, Mahesh, Sankaranarayana P., Pantanelli, Seth, Hwang, Frank S., Siu, Willie O., Nussenblatt, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276384/
https://ncbi.nlm.nih.gov/pubmed/18230609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708944200
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