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Biosynthesis of the Sesquiterpene Antibiotic Albaflavenone in Streptomyces coelicolor A3(2)

Cytochrome P450 170A1 (CYP170A1) is encoded by the sco5223 gene of the Gram-positive, soil-dwelling bacterium Streptomyces coelicolor A3(2) as part of a two-gene cluster with the sco5222 gene. The SCO5222 protein is a sesquiterpene synthase that catalyzes the cyclization of farnesyl diphosphate to t...

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Detalhes bibliográficos
Main Authors: Zhao, Bin, Lin, Xin, Lei, Li, Lamb, David C., Kelly, Steven L., Waterman, Michael R., Cane, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276382/
https://ncbi.nlm.nih.gov/pubmed/18234666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710421200
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