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Identification of Ligand Specificity Determinants in AgrC, the Staphylococcus aureus Quorum-sensing Receptor

Activation of the agr system, a major regulator of staphylococcal virulence, is initiated by the binding of a specific autoinducing peptide (AIP) to the extracellular domain of AgrC, a classical receptor histidine protein kinase. There are four known agr specificity groups in Staphylococcus aureus,...

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Detalhes bibliográficos
Main Authors: Geisinger, Edward, George, Elizabeth A., Muir, Tom W., Novick, Richard P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276371/
https://ncbi.nlm.nih.gov/pubmed/18222919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710227200
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