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Computational Models of Tandem Src Homology 2 Domain Interactions and Application to Phosphoinositide 3-Kinase
Intracellular signal transduction proteins typically utilize multiple interaction domains for proper targeting, and thus a broad diversity of distinct signaling complexes may be assembled. Considering the coordination of only two such domains, as in tandem Src homology 2 (SH2) domain constructs, giv...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276335/ https://ncbi.nlm.nih.gov/pubmed/18204097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708359200 |
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