Early Steps of a Thymic Tumor in SV40 Transgenic Mice: Hyperplasia of Medullary Epithelial Cells and Increased Mature Thymocyte Numbers Disturb Thymic Export

Bone marrow progenitors migrate to the thymus, where they proliferate and differentiate into immunologically competent T cells. In this report we show that mice transgenic for SV40 T and t antigens under the control of the L-pyruvate kinase promoter develop, in a first step, thymic hyperplasia of bo...

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Main Authors: Nabarra, Bernadette, Martinon, Catherine, Godard, Cécile, Vasseur, Florence, de Ribains, Geoffroy, Miquerol, Lucile, Kahn, Axel, Ezine, Sophie
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2002
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276110/
https://ncbi.nlm.nih.gov/pubmed/15144019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10446670310001593532
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