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Functional Tolerance is Maintained Despite Proliferation of CD4 T Cells after Encounter with Tissue-derived Antigen

Since negative selection in the thymus is incomplete, some self-reactive T cells are able to mature and seed the periphery. To study how these T cells interact following encounter with the self-protein they recognize in the periphery, we have developed an adoptive transfer system in which HEL-specif...

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Autori principali: Ausubel, Lara J., Chodos, Anna, Bekarian, Nyree, Abbas, Abul K., Walker, Lucy S. K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276103/
https://ncbi.nlm.nih.gov/pubmed/12885158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/1044667031000137656
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