Overusage of Mouse DH Gene Segment, DFL16.1, Is Strain-Dependent and Determined by cis-Acting Elements

The DJH structure is of particular importance for diversity in the immunoglobulin heavy chain because it encodes most of CDR3. Here, we investigate mechanisms responsible for generating the DJH structure. We found DFL16.1 was used at a high frequency in normal and transformed pre-B cells (fetal live...

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Main Authors: Atkinson, Michael J., Chang, Yenhui, Celler, Jakub W., Huang, Carol, Paige, Christopher J., Wu, Gillian E.
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 1994
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275935/
https://ncbi.nlm.nih.gov/pubmed/7620320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/1994/80207
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