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3’-(32)P Labeling tRNA with Nucleotidyltransferase for Assaying Aminoacylation and Peptide Bond Formation

The analysis of reactions involving amino acids esterified to tRNAs traditionally uses radiolabeled amino acids. We describe here an alternative assay involving [3’-(32)P] labeled tRNA followed by nuclease digestion and TLC analysis that permits aminoacylation to be monitored in an efficient, quanti...

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Detalhes bibliográficos
Main Authors: Ledoux, Sarah, Uhlenbeck, Olke C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275914/
https://ncbi.nlm.nih.gov/pubmed/18241789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2007.08.001
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