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Defects in Thymocyte Differentiation and Thymocyte- Stromal Interactions in the Trisomy 16 Mouse

We have examined fetal thymic development in the trisomy 16 (Ts16) mouse, which is considered to be a model for human trisomy 21, or Down Syndrome. The Ts16 thymus contains 10 to 20% of the number of lymphocytes found in a normal thymus at a comparable stage. Expression of thymocyte differentiation...

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Detalhes bibliográficos
Main Authors: Ewart, Janet L., Auerbach, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275860/
https://ncbi.nlm.nih.gov/pubmed/1378332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/1992/72627
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