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The Lentiviral Integrase Binding Protein LEDGF/p75 and HIV-1 Replication

Retroviral replication proceeds through a stable proviral DNA intermediate, and numerous host cell factors have been implicated in its formation. In particular, recent results have highlighted an important role for the integrase-interactor lens epithelium-derived growth factor (LEDGF)/p75 in lentivi...

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Autors principals: Engelman, Alan, Cherepanov, Peter
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275779/
https://ncbi.nlm.nih.gov/pubmed/18369482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000046
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