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Analysis of Beta-Tubulin Gene Exon 4 Mutations in Advanced Stage III or IV Gastric Cancer

The mechanisms that cause chemoresistance of gastric cancer have yet to be elucidated. Taxanes and promising agents that were recently approved for treatment of advanced or recurrent gastric cancer. Mutations of beta-tubulin, which is a target of taxianes, have been shown to confer chemoresistance a...

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Detalhes bibliográficos
Main Authors: Tahara, Tomomitsu, Arisawa, Tomiyasu, Shibata, Tomoyuki, Hirata, Ichiro, Nakano, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: the Society for Free Radical Research Japan 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275766/
https://ncbi.nlm.nih.gov/pubmed/18398498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.40.210
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