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Analysis of Beta-Tubulin Gene Exon 4 Mutations in Advanced Stage III or IV Gastric Cancer

The mechanisms that cause chemoresistance of gastric cancer have yet to be elucidated. Taxanes and promising agents that were recently approved for treatment of advanced or recurrent gastric cancer. Mutations of beta-tubulin, which is a target of taxianes, have been shown to confer chemoresistance a...

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Autors principals: Tahara, Tomomitsu, Arisawa, Tomiyasu, Shibata, Tomoyuki, Hirata, Ichiro, Nakano, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: the Society for Free Radical Research Japan 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275766/
https://ncbi.nlm.nih.gov/pubmed/18398498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.40.210
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