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Pore Mutations of the Escherichia coli MscS Channel Affect Desensitization but Not Ionic Preference

Mechanosensitive channels rescue bacterial cells from a fate of lysis when they transfer from a high- to low-osmolarity environment. Of three Escherichia coli mechanosensitive proteins studied to date, only MscS-Ec demonstrates a small anionic preference and a desensitized, nonconducting state under...

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Detalhes bibliográficos
Main Authors: Edwards, Michelle D., Bartlett, Wendy, Booth, Ian R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275705/
https://ncbi.nlm.nih.gov/pubmed/18065458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.123448
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