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Impact of Hapten Presentation on Antibody Binding at Lipid Membrane Interfaces

We report the effects of ligand presentation on the binding of aqueous proteins to solid supported lipid bilayers. Specifically, we show that the equilibrium dissociation constant can be strongly affected by ligand lipophilicity and linker length/structure. The apparent equilibrium dissociation cons...

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書誌詳細
主要な著者: Jung, Hyunsook, Yang, Tinglu, Lasagna, Mauricio D., Shi, Jinjun, Reinhart, Gregory D., Cremer, Paul S.
フォーマット: Artigo
言語:Inglês
出版事項: The Biophysical Society 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275692/
https://ncbi.nlm.nih.gov/pubmed/18199665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.115519
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