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Impact of Hapten Presentation on Antibody Binding at Lipid Membrane Interfaces
We report the effects of ligand presentation on the binding of aqueous proteins to solid supported lipid bilayers. Specifically, we show that the equilibrium dissociation constant can be strongly affected by ligand lipophilicity and linker length/structure. The apparent equilibrium dissociation cons...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275692/ https://ncbi.nlm.nih.gov/pubmed/18199665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.115519 |
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