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Hed1 regulates Rad51-mediated recombination via a novel mechanism

Two RecA orthologs, Rad51 and Dmc1, mediate homologous recombination in meiotic cells. During budding yeast meiosis, Hed1 coordinates the actions of Rad51 and Dmc1 by down-regulating Rad51 activity. It is thought that Hed1-dependent attenuation of Rad51 facilitates formation of crossovers that are n...

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Bibliografiset tiedot
Päätekijät: Busygina, Valeria, Sehorn, Michael G., Shi, Idina Y., Tsubouchi, Hideo, Roeder, G. Shirleen, Sung, Patrick
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275431/
https://ncbi.nlm.nih.gov/pubmed/18347097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1638708
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