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DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination
The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and Artemis are classical nonhomologous DNA end-joining (C-NHEJ) factors required for joining a subset of DNA double-strand breaks (DSB), particularly those requiring end processing. In mature B cells, activation-induced cytidine deaminas...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275379/ https://ncbi.nlm.nih.gov/pubmed/18316419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080044 |
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