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Intrathymic expression of Flt3 ligand enhances thymic recovery after irradiation

Hematopoietic stem cell transplantation (HSCT) requires conditioning treatments such as irradiation, which leads to a severely delayed recovery of T cell immunity and constitutes a major complication of this therapy. Currently, our understanding of the mechanisms regulating thymic recovery is limite...

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Autors principals: Kenins, Linda, Gill, Jason W., Boyd, Richard L., Holländer, Georg A., Wodnar-Filipowicz, Aleksandra
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275376/
https://ncbi.nlm.nih.gov/pubmed/18299401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20072065
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