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Exendin-4 Modulates Diabetes Onset in Nonobese Diabetic Mice

Activation of the glucagon-like peptide-1 receptor (GLP-1R) is associated with expansion of β-cell mass due to stimulation of cell proliferation and induction of antiapoptotic pathways coupled to β-cell survival. Although the GLP-1R agonist Exenatide (exendin-4) is currently being evaluated in subje...

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Bibliografiske detaljer
Main Authors: Hadjiyanni, Irene, Baggio, Laurie L., Poussier, Philippe, Drucker, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: The Endocrine Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275367/
https://ncbi.nlm.nih.gov/pubmed/18063685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1137
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