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Exendin-4 Modulates Diabetes Onset in Nonobese Diabetic Mice
Activation of the glucagon-like peptide-1 receptor (GLP-1R) is associated with expansion of β-cell mass due to stimulation of cell proliferation and induction of antiapoptotic pathways coupled to β-cell survival. Although the GLP-1R agonist Exenatide (exendin-4) is currently being evaluated in subje...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Endocrine Society
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275367/ https://ncbi.nlm.nih.gov/pubmed/18063685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1137 |
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