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Hypothalamic Phosphatidylinositol 3-Kinase Pathway of Leptin Signaling Is Impaired during the Development of Diet-Induced Obesity in FVB/N Mice

Phosphatidylinositol 3-kinase (PI3K) pathway of leptin signaling plays an important role in transducing leptin action in the hypothalamus. Obesity is usually associated with resistance to the effect of leptin on food intake and energy homeostasis. Although central leptin resistance is thought to be...

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Bibliografiske detaljer
Main Authors: Metlakunta, Anantha S., Sahu, Maitrayee, Sahu, Abhiram
Format: Artigo
Sprog:Inglês
Udgivet: The Endocrine Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275357/
https://ncbi.nlm.nih.gov/pubmed/18048492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1307
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