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Hypothalamic Phosphatidylinositol 3-Kinase Pathway of Leptin Signaling Is Impaired during the Development of Diet-Induced Obesity in FVB/N Mice

Phosphatidylinositol 3-kinase (PI3K) pathway of leptin signaling plays an important role in transducing leptin action in the hypothalamus. Obesity is usually associated with resistance to the effect of leptin on food intake and energy homeostasis. Although central leptin resistance is thought to be...

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Detalhes bibliográficos
Main Authors: Metlakunta, Anantha S., Sahu, Maitrayee, Sahu, Abhiram
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275357/
https://ncbi.nlm.nih.gov/pubmed/18048492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1307
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