Using Generalized Procrustes Analysis (GPA) for normalization of cDNA microarray data

BACKGROUND: Normalization is essential in dual-labelled microarray data analysis to remove non-biological variations and systematic biases. Many normalization methods have been used to remove such biases within slides (Global, Lowess) and across slides (Scale, Quantile and VSN). However, all these p...

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Bibliographic Details
Main Authors: Xiong, Huiling, Zhang, Dapeng, Martyniuk, Christopher J, Trudeau, Vance L, Xia, Xuhua
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Methodology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275243/
https://ncbi.nlm.nih.gov/pubmed/18199333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-25
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