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Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6

Atopic dermatitis (AD) is characterized by a defective skin barrier which allows increased allergen and pathogen penetration. Loricrin (LOR) and involucrin (IVL) are proteins important for skin barrier formation and integrity. In this study, we demonstrate that the gene and protein expression of LOR...

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Detalhes bibliográficos
Main Authors: Kim, Byung Eui, Leung, Donald Y.M., Boguniewicz, Mark, Howell, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275206/
https://ncbi.nlm.nih.gov/pubmed/18166499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2007.11.006
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