Th2 cytokines increase Staphylococcus aureus alpha toxin induced keratinocyte death through the signal transducer and activator of transcription 6 (STAT6)

Atopic dermatitis (AD) is an inflammatory skin disease characterized by increased Th2 cytokine expression. AD skin lesions are often exacerbated by Staphylococcus aureus mediated secretion of the lytic virulence factor, alpha toxin. In the current study, we report that alpha toxin induced cell death...

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Autors principals: Brauweiler, Anne M, Goleva, Elena, Leung, Donald Y.M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102636/
https://ncbi.nlm.nih.gov/pubmed/24468745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.43
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