The use of multiple displacement amplification to amplify complex DNA libraries

Complex libraries for genomic DNA and cDNA sequencing analyses are typically amplified using bacterial propagation. To reduce biases, large numbers of colonies are plated and scraped from solid-surface agar. This process is time consuming, tedious and limits scaling up. At the same time, multiple di...

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Bibliographic Details
Main Authors: Fullwood, Melissa J., Tan, Jack J. S., Ng, Patrick W. P., Chiu, Kuo Ping, Liu, Jun, Wei, Chia Lin, Ruan, Yijun
Format: Artigo
Language:Inglês
Published: Oxford University Press 2008
Subjects:
Methods Online
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275127/
https://ncbi.nlm.nih.gov/pubmed/18285362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn074
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