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Thermodynamic characterization of specific interactions between the human Lon protease and G-quartet DNA
Lon is an ATP-powered protease that binds DNA. However, the function of DNA binding by Lon remains elusive. Studies suggest that human Lon (hLon) binds preferentially to a G-rich single-stranded DNA (ssDNA) sequence overlapping the light strand promoter of mitochondrial DNA. This sequence is contain...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275097/ https://ncbi.nlm.nih.gov/pubmed/18174225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1140 |
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