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Distinct protein domains regulate ciliary targeting and function of C. elegans PKD-2
TRPP2 (transient receptor potential polycystin-2) channels function in a range of cells where they are localized to specific subcellular regions including the endoplasmic reticulum (ER) and primary cilium. In humans, TRPP2/PC-2 mutations severely compromise kidney function and give rise to autosomal...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275051/ https://ncbi.nlm.nih.gov/pubmed/18037411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.10.017 |
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