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Casein Kinase II and Calcineurin Modulate TRPP Function and Ciliary Localization

Cilia serve as sensory devices in a diversity of organisms and their defects contribute to many human diseases. In primary cilia of kidney cells, the transient receptor potential polycystin (TRPP) channels polycystin-1 (PC-1) and polycystin-2 (PC-2) act as a mechanosensitive channel, with defects re...

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Detalhes bibliográficos
Main Authors: Hu, Jinghua, Bae, Young-Kyung, Knobel, Karla M., Barr, Maureen M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1446073/
https://ncbi.nlm.nih.gov/pubmed/16481400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-10-0935
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