Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome

We prospectively observed a child exposed to intensive multimodality therapy for metastatic neuroblastoma from emergence of a MLL translocation to disease diagnosis. The t(4;11)(p12;q23) was detected in the marrow 17 months after starting treatment following topoisomerase II poisons, alkylating agen...

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Detalhes bibliográficos
Main Authors: Robinson, Blaine W., Cheung, Nai-Kong V., Kolaris, Christos P., Jhanwar, Suresh C., Choi, John K., Osheroff, Neil, Felix, Carolyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275033/
https://ncbi.nlm.nih.gov/pubmed/18195096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-096065
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