The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis

Ultralarge von Willebrand factor (UL-VWF) multimers are thought to play a central role in pathogenesis of the disease thrombotic thrombocytopenic purpura (TTP); however, experimental evidence in support of this hypothesis has been difficult to establish. Therefore, to examine directly the requiremen...

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Bibliographic Details
Main Authors: Chauhan, Anil K., Walsh, Meghan T., Zhu, Guojing, Ginsburg, David, Wagner, Denisa D., Motto, David G.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2008
Subjects:
Hemostasis, Thrombosis, and Vascular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275014/
https://ncbi.nlm.nih.gov/pubmed/18083848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-08-108571
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