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Glucocorticoid Regulation of Human Pulmonary Surfactant Protein-B mRNA Stability Involves the 3′-Untranslated Region

Expression of pulmonary surfactant, a complex mixture of lipids and proteins that acts to reduce alveolar surface tension, is developmentally regulated and restricted to lung alveolar type II cells. The hydrophobic protein surfactant protein-B (SP-B) is essential in surfactant function, and insuffic...

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Autores principales: Huang, Helen W., Bi, Weizhen, Jenkins, Gaye N., Alcorn, Joseph L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2274950/
https://ncbi.nlm.nih.gov/pubmed/18006875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0303OC
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