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Drosophila Ebi mediates Snail-dependent transcriptional repression through HDAC3-induced histone deacetylation
The Drosophila Snail protein is a transcriptional repressor that is necessary for mesoderm formation. Here, we identify the Ebi protein as an essential Snail co-repressor. In ebi mutant embryos, Snail target genes are derepressed in the presumptive mesoderm. Ebi and Snail interact both genetically a...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2274935/ https://ncbi.nlm.nih.gov/pubmed/18309295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.26 |
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