Assessing the fraction of short-distance tandem splice sites under purifying selection

Many alternative splice events result in subtle mRNA changes, and most of them occur at short-distance tandem donor and acceptor sites. The splicing mechanism of such tandem sites likely involves the stochastic selection of either splice site. While tandem splice events are frequent, it is unknown h...

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Bibliografiska uppgifter
Huvudupphovsmän: Hiller, Michael, Szafranski, Karol, Sinha, Rileen, Huse, Klaus, Nikolajewa, Swetlana, Rosenstiel, Philip, Schreiber, Stefan, Backofen, Rolf, Platzer, Matthias
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2008
Ämnen:
Bioinformatics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271360/
https://ncbi.nlm.nih.gov/pubmed/18268022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.883908
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