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Assessing the fraction of short-distance tandem splice sites under purifying selection

Many alternative splice events result in subtle mRNA changes, and most of them occur at short-distance tandem donor and acceptor sites. The splicing mechanism of such tandem sites likely involves the stochastic selection of either splice site. While tandem splice events are frequent, it is unknown h...

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Hlavní autoři: Hiller, Michael, Szafranski, Karol, Sinha, Rileen, Huse, Klaus, Nikolajewa, Swetlana, Rosenstiel, Philip, Schreiber, Stefan, Backofen, Rolf, Platzer, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271360/
https://ncbi.nlm.nih.gov/pubmed/18268022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.883908
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