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Probing the Mechanisms of DEAD-box Proteins as General RNA Chaperones: The C-terminal Domain of CYT-19 Mediates General Recognition of RNA

The DEAD-box protein CYT-19 functions in folding of several group I introns in vivo and a diverse set of group I and group II RNAs in vitro. Recent work using the Tetrahymena group I ribozyme demonstrated that CYT-19 possesses a second RNA binding site, distinct from the unwinding active site, which...

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Detalhes bibliográficos
Main Authors: Grohman, Jacob K., Campo, Mark Del, Bhaskaran, Hari, Tijerina, Pilar, Lambowitz, Alan M., Russell, Rick
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271177/
https://ncbi.nlm.nih.gov/pubmed/17311413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0619472
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