Tumor-Specific Hsp70 Plasma Membrane Localization Is Enabled by the Glycosphingolipid Gb3

BACKGROUND: Human tumors differ from normal tissues in their capacity to present Hsp70, the major stress-inducible member of the HSP70 family, on their plasma membrane. Membrane Hsp70 has been found to serve as a prognostic indicator of overall patient survival in leukemia, lower rectal and non smal...

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Main Authors: Gehrmann, Mathias, Liebisch, Gerhard, Schmitz, Gerd, Anderson, Robin, Steinem, Claudia, De Maio, Antonio, Pockley, Graham, Multhoff, Gabriele
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2008
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Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271151/
https://ncbi.nlm.nih.gov/pubmed/18382692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001925
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