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Targeted inactivation of the COP9 signalosome impairs multiple stagesof T cell development
Genetic programs promoting cell cycle progression, DNA repair, and survival are coordinately induced in developing T cells and require rapid turnover of effector molecules. As the COP9 signalosome (CSN) has been placed at the crossroads of these programs in lower organisms, we addressed its role by...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2271025/ https://ncbi.nlm.nih.gov/pubmed/18268034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070725 |
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