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CTLA-4 Engagement Inhibits Th2 but not Th1 Cell Polarisation
CTLA-4 deficient mice show severe lymphoproliferative disorders with T helper sub-population skewed toward the Th2 phenotype. In the present work, we investigated the role of CTLA-4 in T helper cell subset differentiation. Naïve CD4(+) cells were stimulated with anti-CD3 and anti-CD28 mAbs in the pr...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Hindawi Publishing Corporation
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2270672/ https://ncbi.nlm.nih.gov/pubmed/14575153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10446670310001598519 |
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