Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes

BACKGROUND/HYPOTHESIS: HLA, INS, PTPN22 and CTLA4 are considered to be confirmed type 1 diabetes susceptibility genes. HLA, PTPN22 and CTLA4 are known to be involved in immune regulation. Few studies have systematically investigated the joint effect of multiple genetic variants. We evaluated joint e...

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Main Authors: Bjørnvold, M., Undlien, D. E., Joner, G., Dahl-Jørgensen, K., Njølstad, P. R., Akselsen, H. E., Gervin, K., Rønningen, K. S., Stene, L. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270365/
https://ncbi.nlm.nih.gov/pubmed/18292987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-008-0932-0
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