Ca(2+) store dynamics determines the pattern of activation of the store-operated Ca(2+) current I(CRAC) in response to InsP(3) in rat basophilic leukaemia cells

1. I(CRAC) and intracellular inositol 1,4,5-trisphosphate (InsP(3)) concentration is complex. In rat basophilic leukaemia (RBL-1) cells dialysed with high intracellular Ca(2+) buffer, the relationship is supra-linear with a Hill coefficient of 12 and resembles an apparent ‘all-or-none’ phenomenon. T...

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Bibliographic Details
Main Authors: Glitsch, Maike D, Parekh, Anant B
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2000
Subjects:
Rapid Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269810/
https://ncbi.nlm.nih.gov/pubmed/10699074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-2-00283.x
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