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Ca(2+) store dynamics determines the pattern of activation of the store-operated Ca(2+) current I(CRAC) in response to InsP(3) in rat basophilic leukaemia cells

1. I(CRAC) and intracellular inositol 1,4,5-trisphosphate (InsP(3)) concentration is complex. In rat basophilic leukaemia (RBL-1) cells dialysed with high intracellular Ca(2+) buffer, the relationship is supra-linear with a Hill coefficient of 12 and resembles an apparent ‘all-or-none’ phenomenon. T...

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Detalhes bibliográficos
Main Authors: Glitsch, Maike D, Parekh, Anant B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269810/
https://ncbi.nlm.nih.gov/pubmed/10699074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-2-00283.x
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