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Kinetic and mutational analysis of Zn(2+) modulation of recombinant human inhibitory glycine receptors
1. The effects of Zn(2+) on glycine receptor (GlyR) currents were analysed in Xenopus oocytes and human embryonic kidney cells expressing homomeric human wild-type and mutant α1 subunit GlyRs. 2. Low concentrations (10 μm) of extracellular Zn(2+) converted the partial agonist taurine into a high-eff...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2269758/ https://ncbi.nlm.nih.gov/pubmed/10639099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-1-00215.x |
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